IMMUNOLOGICAL PREDICTORS OF RENAL GRAFT REJECTION IN THE EARLY POSTOPERATIVE PERIOD

Objective. To determine the immunological predictors of renal graft rejection in early postoperative period. Methods. Three groups were formed out 197 recipients. The group PGF (n=101) was made up patients with satisfactory primary function. PGD (n = 82) included dysfunction without episodes rejection. RGR (n=14) consisted and On 7<sup>th</sup> day after transplantation kidney function assessed on basis ofserum creatinine levels. When serum value lower than 300 μmol/L considered to be primary, at a concentration equal or higher μmol/L, as well case needfor maintenance dialysis first week transplantation, state classified dysfunction. In period, number LIN-HLA-DR+ dendritic cells LIN-HLA-DR+CD11c+CD123- LIN-HLA-DR+CD11c-CD123+ phenotypes fluid from drainage installed during surgery determined. Predictive characteristics mDC pDC levels determined predict rejection, diagnostic capability this indicator identified. Results. It has been revealed that is characterized by significant growth total fluid, mainly due myeloid ones. level plasmacytoid fluid. cut-off point 60.32%, for it corresponded 39.68%. Conclusion. With greater 39.68%, predicted sensitivity 99% 93%, respectively, specificity 89% 91%, respectively. What paper adds their subpopulations recipients firstly studied. established acute associated high More over increase occurs cells. determination can used predictor